This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Feng Zhang, a leader in the development of this technology, is a faculty member at MIT, an investigator at the McGovern Institute for Brain Research, and a core member of the Broad Institute.
Over the nine years since Sabatini’s talk, lysosomes have won more respect. Research continues to show that lysosomes transcend the trash can role, acting as crucial advisers to the nucleus in its job of genetic…Read More
"There is also a deeper message laid bare within our futurist projections. Our notions about the emergence of intelligent machines expose our fantasies (often unspoken) about what perfection is: not soft and biological,…Read More
What principal component analysis (PCA) does is, it takes an individual’s genetic data and boils it down to just a few numbers. In learning about how this method works — its strengths and its weaknesses —…Read More
Studies have suggested the genius physicist might have had a larger corpus callosum connecting his hemispheres, larger ratio of 'helper' glial cells to neurons, and an unusual size and pattern of grooves on…Read More
How can humans be so compassionate and altruistic — and also so brutal and violent? To understand why we do what we do, neuroscientist Robert Sapolsky looks at extreme context, examining actions on timescales from…Read More
